Researchers have identified a previously unknown biological process that causes tissue and organ damage in conditions where ...

In light of these concepts, current massive transfusion protocols incorporate hemostasis-directed resuscitation, or the pre-emptive administration of blood coagulation products along with packed ...

THN391 has the potential to be a first-in-class antibody that can block fibrin-mediated neuroinflammation without affecting coagulation pathways, and recently completed a phase 1ba trial in ...

COVID-19 is characterized by dysregulated thrombosis and coagulation that can increase mortality in ... the contribution of the virus to programmed cell death pathway activation in platelets and the ...

The role of APC in hyperoxic acute lung injury was tested by studying the physiology of lung injury development, measurement of key coagulation proteins and treatment with murine APC (mAPC). Methods: ...

Due to their dual activity, the contact-kinin pathway not only triggers thrombus formation by activating intrinsic coagulation via FXI (factor XI) but is also involved in the regulation of ...

Methods: A cold-coagulation type dysmenorrhea model was established in ... their anti-inflammatory and analgesic effects by activating the COX-2/mPGES-1/PGE2 pathway and mediating the increased ...