Christina Applegate has shared another brutally honest update about her debilitating battle with multiple sclerosis (MS). The 53-year-old was diagnosed with the autoimmune disease, which damages ...

Christina Applegate attends the Screen Actors Guild Awards on Jan. 19, 2020. She also recalled that her first symptom was her toes beginning to feel numb in January 2021.

Swisher then said she was very sad when one of her parents died adding it left her in an unusual state. Applegate noticed the first signs of MS after 'falling' on her series Dead To Me.

During a recent episode of "MeSsy, " the podcast she shares with actress Jamie-Lynn Sigler, Applegate revealed that she has been hospitalized "upwards of 30 times" due to intense MS symptoms.

Example: Christina Applegate guest stars in two episodes of “Friends” as Amy Green, Rachel’s sister, who takes her niece to get her ears pierced without obtaining the go-ahead from her parents.

Christina Applegate owes it all to her former TV dad, Ed O’Neill. Applegate, 52, reunited with O’Neill, 78, on Tuesday’s episode of her “MeSsy” podcast and they gushed over their ...

On the “Messy with Christina Applegate & Jamie-Lynn Sigler” podcast, Applegate revealed the comment that inspired her to undergo surgery in her 20s.

Christina Applegate is doing just fine, okay? Well, not really. But she's being honest about it, and that's helping her to deal with her multiple sclerosis. "This is being really honest: I don't ...

Christina Applegate says the return of her depression is scaring her 'because it feels really fatalistic' as she details the mental toll of her MS battle.

Christina Applegate is opening up about living with depression after her MS diagnosis. The Married with Children alum got candid about her mental health on the latest episode of her podcast. “A ...

Now, Applegate said she's "kind of just giving up" with everything, save for Sadie, the 13-year-old daughter she shares with her husband, Martyn LeNoble. "You know me," Applegate told Sigler.

Christina Applegate is done trying to filter herself. The beloved actress — known for her hilarious wit and tremendous talent — recently participated in an inspirational, heartfelt panel at ...