Christina Applegate revealed in a new episode of her podcast that she has been hospitalized "upwards of 30 times" due to MS symptoms.

Want to become an actor? Before you start applying for parts, it’s important to understand the different types of acting roles.

Christina Applegate reunited with Ed O'Neill, who played her dad on "Married... with Children," on her "MeSsy" podcast.

On the “Messy with Christina Applegate & Jamie-Lynn Sigler” podcast, Applegate revealed the comment that inspired her to undergo surgery in her 20s.

This article originally appeared on USA TODAY: 'Anchorman' turns 20: The 10 best Will Ferrell movies, ranked ...

Christina Applegate's only child, Sadie, spoke out about her POTS diagnosis and how it helps her understand her mom's MS symptoms.

Christina Applegate clarifies 'I don't enjoy living' comment: 'I'm not sitting here on suicide watch' Applegate says she's just being honest about what she's going through since being diagnosed ...

Christina Applegate says the return of her depression is scaring her 'because it feels really fatalistic' as she details the mental toll of her MS battle.

Christina Applegate is opening up about living with depression after her MS diagnosis. The Married with Children alum got candid about her mental health on the latest episode of her podcast. “A ...

Christina Applegate is done trying to filter herself. The beloved actress — known for her hilarious wit and tremendous talent — recently participated in an inspirational, heartfelt panel at ...

Christina Applegate revealed that she could have been a cast member on The Real Housewives of Beverly Hills. On the most recent episode of her podcast, MeSsy, which she co-hosts with Jamie-Lynn ...

Christina Applegate details painful MS relapse, hasn't slept for 24 hours or showered for 3 weeks Applegate discussed her symptoms on her podcast, "MeSsy," co-hosted by Jamie-Lynn Sigler.