Chlorambucil may be effective in some cases. Methotrexate is used for biopsy-confirmed sclerosing cholangitis. It is important to maintain adequate nutrition to prevent secondary hepatic lipidosis.

Knauf WU, Lissichkov T, Aldaoud A, et al: Phase III randomized study of bendamustine compared with chlorambucil in previously untreated patients with chronic lymphocytic leukemia. J Clin Oncol 27:4378 ...

DelveInsight’s, “Chronic Lymphocytic Leukemia Pipeline Insight 2025” report provides comprehensive insights about 55+ companies and 60+ pipeline drugs in Chronic Lymphocytic Leukemia (CLL) pipeline ...

In this study, the synthesis, characterization, density functional theory calculations (DFT), and effect of polyethylenimine (PEI)-functionalized nitrogen-doped graphene quantum dots (PEI N-GQDs) and ...

Itchy skin (pruritus) without a rash may be caused by dry skin, allergies, bug bites, or an underlying medical condition.Health issues like liver disease, kidney disease, and thyroid disorders can all ...

We describe a novel synthetic small molecule which shows an unprecedented stabilization of the human telomeric G-quadruplex with high selectivity relative to double-stranded DNA. We report that this ...