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A Hong Kong University of Science and Technology (HKUST) research team has developed a catalytic enantioselective type II ...
Thus, developing a chemical synthesis reaction that selectively produces one enantiomer of chiral molecules useful in medicine is of great significance in the synthesis of drugs and their precursors.
Enantiomers, or molecule pairs that are mirror images of each other, make up more than half of FDA-approved drugs in use ...
Scientists at The Scripps Research Institute (TSRI) say they have invented a new technique for constructing chiral drug molecules, whose structural complexity allows them to have mirror-image ...
Chiral molecules are those whose structural complexity allows them to have mirror-image, "left-handed" and "right-handed" forms. For drug molecules, usually only one of those forms works - the ...
At the time, large-scale asymmetric synthesis was impractical, so development of single-isomer drugs had to rely on inefficient chiral resolution. More recently, even with the emergence of new ...
Twisted vibrations enable quality control for chiral drugs and supplements. ScienceDaily . Retrieved May 30, 2025 from www.sciencedaily.com / releases / 2022 / 03 / 220321132157.htm ...
Researchers have been actively looking for novel antitubercular medications with little side effects that are effective against drug-resistant strains to solve this problem. The usage of chiral drugs ...
One prominent example of a chiral switch occurred in 2001, when the US Food and Drug Administration (FDA) approved AstraZeneca’s esomeprazole (Nexium), a proton pump inhibitor (PPI) used to ...
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