G protein-coupled receptors (GPCRs) represent the targets of more than 30% of the drugs currently on the market. However, ...

The transfer of electrons through protein complexes is central to cellular respiration. Exploiting proteins for charge transfer in a controllable fashion has the potential to revolutionize the ...

Unfolded proteins can bind to the lumen domain of Ire1, thereby triggering the self-binding of Ire1 and activating its cytoplasmic effector domain (Credle et al., 2005; Pincus et al., 2010). Proper ER ...

Extracellular chaperones modulate the effects of Alzheimer’s patient cerebrospinal fluid on Aβ1-42 toxicity and uptake. Cell Stress and Chaperones 2010, 15 (1) , 115-121. DOI: ...