Molecular chaperones play a pivotal role in ensuring proper cellular protein homeostasis through their involvement in protein ...

Emerging research positions TUDCA, a bile acid compound, as a promising neuroprotective agent against Alzheimer’s, ...

How proteins in our cells attain their correct three-dimensional structure is crucial to their function—and to our health.

How proteins in our cells attain their correct three-dimensional structure is crucial to their function—and to our health. Errors in this process can lead to serious diseases. Researchers at the ...

A master of protein origami Johns Hopkins chemist Stephen Fried has spent decades investigating how protein cells fold, unfold, and misfold, a cause of many neurodegenerative diseases and our ...

Proteins need to fold into specific three-dimensional shapes to function correctly. Among their several roles, chaperone proteins like Hsp70s typically assist the correct folding of proteins. To ...

A protein called PAR1 helps lymphatic vessels structurally transform to boost fluid drainage and support healing when the ...

Scientists identified a nuclear mechanism that distinguishes chronic inflammation from acute inflammation in mice.

Brain's immune cells, microglia, are constantly renewed. New research reveals a key gene, pu.1, partners with the "guardian of the genome" gene Tp53. They ensure only the fittest microglia survive by ...