This study presents compelling evidence that the denitrosylase SCoR2 regulates cardioprotective metabolic reprogramming in the heart following ischemia/reperfusion injury. The findings are supported ...

The Cyto-Mine Chroma platform uses fluorescence-based assays in picodroplets to select single cells based on secreted, surface, and/or intracellular markers. Aided by the new multiplexing capability ...

Here, we describe the development of a new panel of biochemical and cell-based assays to evaluate the binding and function of known chemical entities targeting mutant KRAS. Our assay panels generated ...

Therefore, image-based profiling allows researchers to make discoveries free of bias. The Cell Painting assay has become one of the most ... difference between cells from patients with a disease ...

The increase in disease burden, and the corresponding economic burden, has led to the growing use of cell-based assays ... data can be utilized to validate biochemical data and can reveal unknown ...

6 The National Taiwan University Hospital (NTUH) is one of the study sites for BFAST, and the blood-based NGS assay provided genomic alteration results for the enrolled patients. Our study aimed to ...

Measuring functional antibody blockade of the spike protein/ACE2 interaction is therefore likely to become increasingly important, and we envisage that this cell-based, spike protein interaction assay ...

among 3 assays used in suspected cases of myasthenia gravis. “Thus, the current guidelines for the diagnosis of MG generally lack evidence-based recommendations on methodology for detecting AChR ...