Pathway-focused metabolite ratio-based analysis of 49 tumor and 8 normal epithelial cell lines grown in their respective ...

Abstract: This work demonstrated a novel dual-aptamer assay performed on a paper-based membrane composed of nitro-cellulose (NC) on an integrated microfluidic platform for detection of a biomarker, ...

Endogenous intracellular allosteric modulators of GPCRs remain largely unexplored, with limited binding and phenotype data available. This gap arises from the lack of robust computational methods for ...

Objectives: We investigated whether the acetylcholine receptor (AChR) cluster cell-based assay (CBA) is effective in detecting AChR antibodies in sera from myasthenia gravis (MG) patients with low ...

Large-scale comparison of gene families across 1154 Saccharomycotina genomes revealed that gene gains and losses drive yeast ...

This landmark study describes the structure of the human RAD51 filament with a recombination intermediate called the displacement loop (D-loop). Using cryogenic structural, biochemical, and ...

Resazurin dye has been broadly used as indicator of cell viability in several types of assays for evaluation of the biocompatibility ... Thus, our aim was to develop a simple, cheap and precise method ...

Department of Pharmaceutics, The School of Pharmacy, Fujian Medical University, Fuzhou, Fujian Province 350122, PR China Innovative Drug Research Institute, Fujian Medical University, Fuzhou, Fujian ...

About the VENTANA MET (SP44) RxDx Assay The VENTANA MET (SP44) RxDx Assay detects the MET protein and is scored by pathologists based on the percentage of tumour cells stained and the intensity of the ...

This study aimed to evaluate the efficacy and safety of nedaplatin (NDP) in comparison to other platinum-based (OPB) agents combined with paclitaxel and concurrent neoadjuvant radiotherapy for locally ...