Myosin makes the moves to keep cell processes humming along by Leah Shaffer, Washington University School of Medicine in St. Louis ...

T. Mizutani, et al., “Diphosphorylation of the Myosin Regulatory Light Chain Enhances the Tension Acting on Stress Fibers in Fibroblasts,” Journal of Cellular ...

In the present version of the manuscript, we use the A21V cells as control cells to determine the effect of heat shock on tissue organisation, actin network, myosin activity and mechanical properties ...

Japanese scientists have designed a new optogenetic tool called OptoMYPT that uses blue light to move a phosphatase enzyme to a location under the cell membrane where it dephosphorylates myosin ...

High cell membrane tension constrains the spread of cancer Findings will contribute towards cancer treatments that target physical characteristics of cells~ Date: November 8, 2021 Source: Kobe ...

All cell functions that involve membrane deformation or a change in cell shape (e.g., endocytosis, exocytosis, cell motility, and cytokinesis) are regulated by membrane tension. While molecular ...

Hair cells can contain hundreds of stereocilia, which rely on myosin motors to elongate, organize, and stabilize their structure. Mutations in many stereocilia-associated myosins have been shown to ...

Non-muscle myosin II plays a role in many fundamental cellular processes including cell adhesion, migration, and cytokinesis. However, its role in vascular function is not well understood. Here, we ...

Biophysical and structural studies reveal how low piconewton forces across actin enhance binding by the critical cell-cell adhesion protein α-catenin versus its force insensitive homolog vinculin.