During animal development, cells divide and arrange themselves in a coordinated way, eventually forming the embryo. The cells ...

Cell Surface Receptors Are All 'Talk' In T Cell Stimulation Date: June 13, 2008 Source: Tufts University, Health Sciences Summary: Using imaging techniques, researchers have revealed the dynamic ...

Lung macrophages play a pivotal role in diseases like idiopathic pulmonary fibrosis. Two types of macrophages—the white blood ...

Based on meta-analysis of over 100 studies of transmembrane cell-surface receptors, experts have proposed a new model for receptor activation -- the "rotation model." If the model proves correct ...

During animal development, cells divide and arrange themselves in a coordinated way, eventually forming the embryo.

Human cells sense and communicate via cell surface receptors on their surface. Information about the environment is relayed to the inside of the cell through dynamic changes in their arrangement ...

To cast a wider net, Rauch adopted a candidate approach. She used the same assay with cells she had denuded of various cell-surface receptors. Specific guide RNAs and CRISPR ensured that H4 ...

Cell-surface receptors are the targets for more than 60% of current drugs. Traditionally, optimizing the interaction of lead molecules with the binding site for the endogenous agonist (orthosteric ...

Triggering receptors expressed on myeloid cells (TREMs) are a cell surface receptor family found on granulocytes, monocytes, macrophages, and dendritic cells—as well as other myeloid cells in general.

Scientists from Tokyo Metropolitan University have realized a new polymer that can effectively transport plasmid DNA into T-cells during chimeric antigen receptor (CAR) T-cell therapy, a key ...

T cells play an essential role defending the body against viruses and bacteria. To mount these defenses, T cells must sense these pathogens via cell surface receptors known as antigen receptors.