The development and spread of antibiotic resistance represents one of the greatest threats to global health. To overcome these resistances, drugs with novel modes of action are urgently needed.

To kill drug-resistant bacteria, “last-resort” antibiotics borrow a tactic from Medusa’s playbook: petrification. New high-resolution microscope images show that a class of antibiotics called ...

About a decade ago, researchers began to observe a recurring challenge in their research: Some of the compounds they were developing to harness energy from bacteria were instead killing the microbes.

In addition to the urgent need for new antibiotics, alternative strategies are required to tackle the problem of antibiotic ...

The electrical potential across the bacterial cell envelope indicates when bacteria no longer operate as individual cells but as a collective. Researchers have discovered this connection between the ...

Bacteria can detect and respond to local cell-surface perturbations, but how they sense changes in overall cell shape and ...

As strains of pathogens resistant to frontline antibiotics become more common worldwide, clinicians are more often turning to combination treatments that degrade this resistance as a first treatment ...

An inexpensive new porous membrane can quickly remove a broad spectrum of antibiotics from wastewater efficiently and without requiring a lot of energy (Matter 2022, DOI: 10.1016/j.matt.2022.09.021).

Scientists at Duke University report they have developed a synthetic antibiotic that could be effective against drug-resistant superbugs and bacteria such as Salmonella, Pseudomonas, and E. coli.

Researchers studying antimicrobial-resistant E. coli – the leading cause of human death due to antimicrobial resistance worldwide – have identified a mechanism in dogs that may render multiple ...