New research by Sumeda Nandadasa, Ph.D., reveals how a key protein associated with Meckel-Gruber syndrome, nephronophthisis, ...

The accurate distribution of chromosomes in an oocyte is essential for the correct transmission of genetic information to the ...

Endocytosis has been the bane of the intracellular delivery efficiency of nanoscale systems. A class of delivery systems, viz., cell membrane-coated nanoparticles (CMNPs), show efficacious and even ...

Glioblastoma multiforme (GBM) is the most common and aggressive malignant brain tumor characterized by poor prognosis and limited treatment options. Despite current therapies combining surgery, ...

Claudin-18 isoform 2 (CLDN18.2) has emerged as a promising therapeutic target in gastric or gastro-oesophageal junction cancer. Satricabtagene autoleucel (satri-cel; also known as CT041), an ...

In particular, rare disease biotechs and those developing complex modalities like cell and gene therapies have urged the Trump administration to provide exemptions to pending pharma tariffs. The pleas ...

Tarlatamab, a bispecific delta-like ligand 3–directed T-cell engager immunotherapy, received accelerated approval for the treatment of patients with previously treated small-cell lung cancer.

These cells can interact with millions of neurons, and for a long time, they were thought to simply provide support. However, new research suggests astrocytes may be doing far more, including playing ...

An H-cell modified with electrodes and an ion-conducting ceramic membrane to conduct sodium-air fuel cell experiments. Credit: Gretchen Ertl High Energy Density Could Enable Electric Flight “We expect ...