Here, I give an overview of the many mitotic kinases that regulate cell division and the fidelity ... Mitotic progression requires that several checkpoints are silenced, the most prominent of ...

The cell must also pass through a series of checkpoints that ensure conditions are favorable for division. In order to move from one phase of its life cycle to the next, a cell must pass through ...

This exhaustion is influenced by immune checkpoint receptors, which are inhibitory cell surface receptors that can suppress antitumor immunity. Notably, intracellular checkpoint molecules within ...

This process can further prolong cell division or introduce structural impairments that ... immune response and increase cancer cells’ sensitivity to drugs like immune checkpoint inhibitors. Other ...

A newly described small molecule inhibitor called AOH-1996 targets a cancer-associated isoform of PCNA (caPCNA), leading to a very broad therapeutic window.

A new study challenges a widely-held notion about cell division. © screenshot from a video by The University of Manchester, with photo editing by Gizmodo If you took ...

The Institute of Cancer Research, London, is seeking partners to continue the development of a cancer biomarker for predicting susceptibility to drugs targeting cell ...

Cell division is the process of a cell splitting into two genetically identical daughter cells. The actin protein seen in this video is essential for successful cell division. While actin has several ...

All cells are produced from other cells by the process of cell division. Cell division occurs when one cell divides to produce two new cells. Unicellular organisms use cell division to reproduce.