CHENNAI: India’s largest drug maker, Sun Pharmaceutical Industries, has completed its acquisition of US-based Checkpoint Therapeutics for approximately $355 mil ...

Centromeres, specialized regions located at the center of chromosomes, are critical for ensuring proper cell division. During ...

In a study published in Proceedings of the National Academy of Sciences , researchers from Queen Mary University of London ...

On May 26 Fort Knox will open its gates to those wishing to visit any of the 122 cemeteries on post in honor of Memorial Day.

aDepartment of Medicine, Division of Hematology, Oncology ... USA fDepartment of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, MN, USA gDepartment of Biomedical ...

Dysregulation of cell cycle checkpoints, which ensure orderly progression through the cell division cycle, can allow cells with DNA damage to proliferate, contributing to genomic instability and ...

Lei Deng, MD, assistant professor in the Division of Hematology ... of care to use dual checkpoint blockade for [patients with STK11 and/or KEAP1 mutations].” The cell line and mouse data ...

Therefore, the importance of checkpoints in the cell cycle lies in their role in maintaining genetic stability, ensuring accurate cell division, and, ultimately, controlling cell growth and ...

In their manuscript "Spindle assembly checkpoint-dependent mitotic delay is required for cell division in absence of centrosomes," Farrell and colleagues employ carefully chosen approaches to assay ...

A newly described small molecule inhibitor called AOH-1996 targets a cancer-associated isoform of PCNA (caPCNA), leading to a very broad therapeutic window.

Department of Medicine (H.Z., S.W., J.W.N., H.A.W., S.A.R., S.S., R.M.W., P.K.N., S.M.W.), Stanford University, CA. Stanford Cardiovascular Institute (H.Z., F.X.G., D ...