Here, I give an overview of the many mitotic kinases that regulate cell division and the fidelity ... Mitotic progression requires that several checkpoints are silenced, the most prominent of ...

The cell must also pass through a series of checkpoints that ensure conditions are favorable for division. In order to move from one phase of its life cycle to the next, a cell must pass through ...

A new study challenges a widely-held notion about cell division. © screenshot from a video by The University of Manchester, with photo editing by Gizmodo If you took ...

Cell division is the process of a cell splitting into two genetically identical daughter cells. The actin protein seen in this video is essential for successful cell division. While actin has several ...

This exhaustion is influenced by immune checkpoint receptors, which are inhibitory cell surface receptors that can suppress antitumor immunity. Notably, intracellular checkpoint molecules within ...

The Institute of Cancer Research, London, is seeking partners to continue the development of a cancer biomarker for predicting susceptibility to drugs targeting cell ...

This process can further prolong cell division or introduce structural impairments that ... immune response and increase cancer cells’ sensitivity to drugs like immune checkpoint inhibitors. Other ...

IDO1 and PDL1 are immune checkpoints with key roles in immune system regulation. Their relevance stems from their ability to suppress T-cell function. T-cells are vital to the body’s immune ...