Mushrooms found in the forests of Bankura and Birbhum in West Bengal could become a game-changer in cancer treatment.

Dr Swapan Kumar Ghosh, a researcher from Bengal, has discovered a cancer-fighting compound in the Astraeus asiaticus mushroom ...

Pyroptosis, a highly inflammatory type of programmed cell death, has garnered attention for its potential in cancer treatment.

In vivo animal experiments demonstrated that L-AuNP@TMT induced ICD and caspase-3/GSDME-mediated cellular pyroptosis in tumor cells under near-infrared irradiation, thereby activating the body's ...

A review of the scientific literature suggests the potential of caspase-4/5 as targets for a broad range of inflammatory diseases, including inflammatory bowel disease, hidradenitis suppurativa ...

Cardiovascular disease (CVD) is the leading cause of death and disease burden worldwide. Macrophages are important components of the internal immune cells, which profoundly affects the internal ...

Mammalian genomes are organized by multi-level folding, yet how this organization contributes to cell type-specific transcription remain unclear. We uncovered that the nuclear protein SATB1 ...

Mechanistically, Mtb Mce3C can bind host cathepsin B (CTSB), a lysosome-derived non-caspase protease that determines cell modalities. This binding inhibits CTSB's protease activity towards BH3 ...