Sulthiame is an investigational, generally well-tolerated oral carbonic anhydrase inhibitor that is designed to restore breathing stability which is often a contributing mechanism in people with OSA.

Some of the mechanisms of the different diuretics are described below: These drugs inhibit the enzyme carbonic anhydrase, which has the effect of decreasing the reabsorption of bicarbonate in the ...

Their further study revealed the related mechanism. The red light regulated the transcription factors of carbonic anhydrase gene expression possibly through the phytochrome mediated COP1-SPA1 ...

By revealing new BBB-crossing mechanisms, a wider range of neuropharmaceutical delivery options can be tailored to individuals with diverse biological profiles. Reference: “Primate-conserved carbonic ...

Carbonic anhydrase IV (CA-IV) enables enhanced brain access from ... In this new study, scientists identified these mechanisms using a multidisciplinary approach that combines the researchers’ ...

and was absent in thylakoids of two mutant lines lacking the gene encoding alpha carbonic anhydrase 5 (αCA5). Using mass spectrometry, we revealed the presence of αCA5 in stromal thylakoid membranes ...

The impossibility of isolating it causes understanding its pathogenic mechanisms to be a complicated task. Recent studies identified 16 proteins with the signal peptide needed to be secreted in the ...

Carbonic anhydrase isozyme CA3 protects cells against oxidative stress. Ectopic expression of murine Ca3, but not Ca2, protects proto-oncogene Evi1 expressing Rat1 fibroblast cells (ca3low) against ...