A recent Cochrane review showed that combination regimens significantly improved tumor response and time to disease progression compared with single-agent chemotherapy, with a modest improvement in ...

JoEllen Zembruski-Ruple, while in the care of New York City’s renowned Memorial Sloan Kettering Cancer Center, swallowed the first three chemotherapy pills to treat her squamous cell carcinoma on Jan.

Capecitabine improved relapse-free survival (hazard ratio, 0.86; 95 percent confidence interval, 0.74 to 0.99; P=0.04) and was associated with significantly fewer adverse events than fluorouracil ...

Capecitabine (Xeloda, Hoffmann–La Roche), an oral prodrug of fluorouracil, has been shown to be efficacious as adjuvant chemotherapy in patients with gastrointestinal cancer. 5–7 However, its ...

Capecitabine is an oral fluoropyrimidine prodrug that is selectively converted within cancer cells to the active drug 5-fluorouracil. Clinical trials have indicated that capecitabine is a safe and ...

Capecitabine is a chemotherapy drug sold under the brand name Xeloda. It’s sometimes used as a treatment for gallbladder cancer.

The capecitabine and temozolomide arm showed double the grade 3-4 toxicity rates compared with the temozolomide arm (45% v 22%, OR [95% CI] = 2.69 [1.28 to 5.68]; Fisher's exact P = .005). Seven ...

The efficacy and safety of capecitabine and bevacizumab in elderly patients with metastatic colorectal cancer (mCRC) considered unsuitable for receiving first-line chemotherapy with an irinotecan ...

For patients who received neratinib plus capecitabine, median OS was 21 months (95% CI, 17.7-23.8) compared with 18.7 months (95% CI, 15.5-21.2) for those who received lapatinib plus capecitabine ...

While capecitabine has some activity in HRPC, as suggested by observed PSA responses, we conclude that it is not worthwhile to investigate capecitabine monotherapy in a phase III trial.

Capecitabine can induce sufficient hemolysis to cause an isolated rise in bilirubin levels (reported in 20–70% of patients), which can often lead to a degree of confusion over appropriate dose ...