The discovery may explain why cutting edge CAR T-cell therapy has managed to revolutionized treatment for blood cancer but ...

Cancer immunotherapy has transformed the treatment landscape by helping the immune system recognize and attack tumors. At the ...

Genetic mutations drive skin cancer – but Cancer Research UK is funding research to uncover why mutations only sometimes lead ...

Researchers working on an incurable blood cancer can now use a new lab model that could make testing potential new treatments ...

Scientists at UC Davis discovered a small genetic difference that could explain why humans are more prone to certain cancers than our primate cousins. The change affects a protein used by immune cells ...

Researchers reconstructed the evolutionary history of cancer cells in two patients, tracing the timeline of the mutation that causes the disease to a cell of origin. In a 63-year-old patient, it ...

"With this work, we can know exactly what the immune system of a particular patient recognized in their cancer to differentiate it from normal cells and attack it," said Antoni Ribas, M.D., Ph.D ...

DNA mutations, which ultimately cause cancer, result from three causes: they’re inherited, they happen randomly as cells divide, or they occur due to environmental factors like smoking.

The rising median age of people around the world has the same effect, since cancer can take decades to develop and therefore ...

There is evidence in both mice and humans that the initial oncogenic mutations in solid tumors occur in stem cells. 11,31–33 In genetic studies involving models of brain cancer, skin cancer, and ...

Cancer-related mutations appear in stem cell derivatives utilized in regenerative medicine. The Hebrew University of Jerusalem. Journal Nature DOI 10.1038/s41587-023-02090-2. Keywords ...