Mitochondria are crucial organelles for cellular homeostasis, regulating processes such as ATP production, reactive oxygen species (ROS) management and Ca2+ signaling.

a group of fat-soluble secosteroids crucial to calcium homeostasis, are essential for the mineralization of bone matrix. Extracellular calcium concentrations are controlled by parathyroid hormone ...

See text for further details. Several players participating in calcium homeostasis have been identified over the last decades. We briefly mention these pathways, although it has to be kept in mind, ...

Patients with gastroesophageal reflux disease (GERD) have an increased risk for tinnitus, according to a study published online Dec. 3 in Scientific Reports. The researchers found that during ...

In the past year, three groups have independently discovered at least 21 mutations in RyR2 (Figure) that are linked to stress-induced sudden cardiac death. 7–9 To date, RyR2 mutations have been ...

Calcium is a vital mineral that is crucial for the health of our bones, teeth, and muscles. Even though it is found in numerous foods, achieving the right amounts purely through diet can be ...

Representative 4-h GCaMP recordings in (A) two male mice and (B) a female mouse across the different stages of the estrous cycle showing high frequency baseline activity and larger increases in ...

2014) and in conditional knock-out mouse (Simon et al., 2004). Cellular calcium homeostasis is intimately dependent on functional mitochondria. Therefore, frataxin overexpression in 3T3-L1 adipocytes ...

5 Induction of adipogenesis was accompanied by a concomitant decrease in TRPV1 expression and decreased capsaicin-mediated calcium influx. In the presence of capsaicin, TRPV1 downregulation was no ...