pacificus compared to C. elegans. They showed that the so-called DBL-1 pathway regulating body morphology appears ... long lived and stress resistant developmental stage called the “dauer” form when ...

Indeed, parasitic nematodes invade their hosts as infective larvae, a stage with striking morphological similarities to the dauer stage of C. elegans. The details of the signaling pathways ...

Figure 2: Role of insulin/IGF-1 and TGF-β pathways in controlling reproductive growth versus dauer development ... Figure 5: Structures of the C. elegans acyl-CoA oxidases ACOX-1.1 and ACOX ...

"Our evidence suggests that DAF-36 works early in a pathway ... the C. elegans reproductive capacity and prevent the organism from going into the immature long-lived larval phase called dauer ...

Additionally, all components of the TGF-β Dauer signaling pathway are required ... further examined the physiological phenotypes of C. elegans with neuronal mitochondrial stress and observed ...

The work, done in the nematode worm C. elegans and detailed in ... cells and what were the molecular pathways involved that caused a worm to enter dauer. "The idea that a single gene mutation ...

By comparison, restoration of DAF-2 or AGE-1 in muscle regulated metabolism but did not reverse the dauer stage or lifespan ... essential functions in C. elegans, and the metabolic and ...

Mutation in mitochondrial gene doubles the lifespan in the worm C. elegans by turning on a detox pathway, researchers report. A mutant worm with a change in one mitochondrial gene produces more ...

An international team increased the life of a nematode worm known as C. elegans by genetically altering two "cellular pathways"—biological signalling systems which cells use to communicate with ...

The study, “Parallel Pathways for Serotonin Biosynthesis and Metabolism in C. elegans,” challenges the existing knowledge of how serotonin is produced and what happens to the neurotransmitter ...