Inside our cells, ribosomes—the tireless "protein factories" of life—have just shown off a new skill they haven't used in ...

Including copeptin measurements for patients diagnosed with hypotonic hyponatremia during admission to the emergency ...

Achieving efficiency through commonalities Liquid-phase peptide synthesis (LPPS) is a particularly important synthesis method in the manufacturing of GnRH analogues, hosting numerous benefits.

Cephalosporin C was rediscovered in 1955 34 and structurally elucidated by chemical degradation studies 35 and X-ray crystallographic analysis in 1961. 36 Its first total synthesis was achieved by ...

CNP (C-type natriuretic peptide) plays a key role in vascular homeostasis, mediating vasodilator, anti-inflammatory, and antiatherogenic actions. Since such processes drive AA, we determined the role ...

The DRiP hypothesis proposes that most peptides that bind to MHC class I molecules are derived from newly synthesized defective proteins. Here, the authors revise this hypothesis and propose that ...

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To further validate the role of de novo serine synthesis in Tregs, we used PHGDH-targeted ASOs and found that genetic knockdown of PHGDH led to augmented Treg differentiation as assessed by FOXP3 ...

2.2. Synthesis of the Antimicrobial Peptide Ctx (Ile 21)-Ha AMP (free carboxylate C-terminus) was synthesized and assembled by standard Fmoc/ t Bu solid-phase peptide synthesis methodologies, with ...