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Science Daily1d
Ultrafast 12-minute MRI maps brain chemistry to spot disease before symptoms
Illinois engineers fused ultrafast imaging with smart algorithms to peek at living brain chemistry, turning routine MRIs into ...
C&EN2d
Determining the Structure of Interfacial Peptide Films: Comparing Neutron Reflectometry and Molecular Dynamics Simulations
The peptides AM1 and Lac21E self-organize into switchable films at an air–water interface. In an earlier study, it was proposed that both AM1 and Lac21E formed monolayers of α-helical peptides based ...
The EMBO Journal3d
Formyl-peptide receptor type 2 activation mitigates heart and lung damage in inflammatory arthritis | EMBO Molecular Medicine
Figure EV1. Formyl peptide receptor 2 (FPR2) expression in cardiac and lung cells. HH + STIA was induced as in Fig. 1. From week 4, mice were treated with either vehicle (100 µl per os daily) or ...
C&EN6d
P-Glycoprotein (ABCB1/MDR1) Controls Brain Penetration and Intestinal Disposition of the PARP1/2 Inhibitor Niraparib | Molecular Pharmaceutics - ACS Publications
Niraparib (Zejula), a selective oral PARP1/2 inhibitor registered for ovarian, fallopian tube, and primary peritoneal cancer treatment, is under investigation for other malignancies, including brain ...