In a comprehensive research study, scientists have uncovered a previously unknown mechanism explaining how neurons survive botulinum neurotoxin type A (BoNT/A) exposure, despite the toxin's ...

What mechanism allows neurons to remain alive while their function is blocked? This question has puzzled researchers since botulinum toxin was first developed for medical use. The current study ...

“Myoxinol fits into a wider trend of using neuropeptides in skincare, which aim to modulate nerve signalling or muscle ...

These findings suggest that temporary suppression of AF inducibility was achieved with botulinum toxin in this canine model, and this might be associated with reduced dispersion of ERP. Although the ...

CSIRO scientists helped develop this insect-resistant cotton variety, using a gene derived from a soil bacteria, Bacillus ...

JERUSALEM, Israel, 20 May 2025 – In a comprehensive Genomic Press research article published today, scientists have uncovered a previously unknown mechanism explaining how neurons survive botulinum ...

Further research is obviously needed to clarify the precise mechanisms underlying these disorders. We suggest that clinicians should be careful when treating patients with mitochondrial cytopathies ...

CTK 01512-2 reproduced the antinociceptive effects of the native toxin not only after the intrathecal but ... activity in the most relevant pain models and its mechanisms of action, highlighting the ...

Pharmacological approaches include topical nitrates and botulinum toxin (BT) which act to reduce anal pressure ... The aims of the present study were to compare the therapeutic effect and lowering ...

Department of Biochemistry and Department of Microbiology and Molecular Genetics, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, Wisconsin 53226, and Departments of Chemistry and ...

and that this phenomenon is independent of any direct effect that cholera toxin has on the adenylate cyclase system. The action of naloxone suggests, but does not prove, that loperamide exerts its ...

Botulinum toxin A formulations show distinct differences in onset and duration of effect in women with glabellar rhytids.