Most people with MS who are treated with formulations of botulinum toxin to manage spasticity report being satisfied, a study ...

Learn how trained medical professionals in Hobart use botulinum toxin to manage jaw clenching, bruxism, and masseter ...

Dystonia involves involuntary muscle contractions, but you're not out of options. Discover how botulinum toxin, DBS, and therapy can restore control.

“Myoxinol fits into a wider trend of using neuropeptides in skincare, which aim to modulate nerve signalling or muscle ...

Botulinum toxin molecular mode of action When the motoneuron action potential depolarises the axon terminal, acetylcholine is released from the cytosol into the synaptic cleft. This acetylcholine ...

This article will review the pharmacology of botulinum toxin type A and its clinical efficacy when used to treat upper limb spasticity after stroke.

Medically reviewed by Mary Choy, PharmD Botox is a brand name for botulinum toxin (specifically onabotulinumtoxinA), a protein produced by the bacteria Clostridium botulinum. In uncontrolled doses or ...

As botulinum toxin injections grow in popularity, it is important for clinicians to understand FDA-approved and off-label uses for the substance.

Produced by Clostridium botulinum, a gram-positive anaerobic bacterium, the botulinum neurotoxin (BoNT) proteins prevent the release of acetylcholine at the cholinergic ends of the peripheral ...

Botulinum toxin (the bacterial toxin that causes botulism in humans) paralyzes muscles by blocking release of the neurotransmitter acetylcholine, the chemical signal that drives muscle contraction ...

In the neuronal cytosol, BTX-A disrupts fusion of the acetylcholine-containing vesicle with the neuronal wall by cleaving the SNAP-25 protein in the synaptic fusion complex.