In this GEN webinar, Dave Lahr, PhD, Senior Director of Bioinformatics at Foghorn Therapeutics, discusses chromatin regulation and epigenetic mechanisms that shape transcriptional responses to ...

Further, studying the mechanism of action helps in determining the optimal conditions for the use of preservatives, such as concentration and exposure time, to ensure their effectiveness while ...

Biomarker data show peripheral inhibition of IL-27 signaling and immune activation in NK and T cells following treatment, consistent with the casdozo preclinical data and mechanism of action.

Bevacizumab has previously demonstrated efficacy in treating endometriosis; however, the required dosage levels are associated with systemic side effects, limiting its use in otherwise healthy young ...

LEO Pharma Presents Late-Breaking Results from Phase 2a Mechanism of Action Trial of Temtokibart + Dupilumab in Moderate-to-Severe Atopic Dermatitis ...

New mechanism of action kills cancer cells Date: August 14, 2024 Source: Ruhr-University Bochum Summary: Conventional cancer drugs work by triggering apoptosis, that is programmed cell death, in ...

Incorporating bevacizumab’s direct cytotoxic effects on tumor cells into its mechanism of action represents not only an academic advancement, but also carries significant implications for its clinical ...

Mechanism of action of the hepatitis B and D virus cell entry inhibitor bulevirtide deciphered Date: April 10, 2024 Source: German Center for Infection Research Summary: Over 12 million people ...

TPST-1120, a PPAR⍺ antagonist, combined with atezolizumab and bevacizumab demonstrated superiority across multiple end points vs atezolizumab (Tecentriq) and bevacizumab (Avastin) for the first-line ...

The lack of an association between the Response Evaluation Criteria in Solid Tumors (RECIST) and survival benefit in patients given bevacizumab might be related to the mechanism of action of this drug ...