While most pharma companies have exited the antibiotics area, Japanese drugmaker Shionogi has stuck with it and has just expanded its pipeline with a deal to buy US biotech Qpex Biopharma.

BLIs are designed to overcome a key resistance mechanism that allows pathogens to protect themselves from cefepime and other antibiotics in the beta-lactam class and have been used to restore acti ...

The study reveals lariocidin, a potent ribosome-targeting antibiotic, with unique mechanisms that could combat drug-resistant bacterial infections effectively.

There are many different types of antimicrobials, each with distinct mechanisms for targeting pathogens and other disease-causing organisms. For example, β-lactam antibiotics such ... to determine the ...

The common compounds identified in all the samples were 3,4-dimethylbenzoic acid (Retention Time/RT = 20.55) and lauryl acetate (RT = 25.64) classified as fatty acid derivatives and caprolactam (RT = ...

The following is a summary of “Impact of aminoglycosides on survival rate and renal outcomes in patients with urosepsis: a ...

The development and spread of antibiotic resistance represents one of the greatest threats to global health. To overcome ...

“This elucidation of MIPLYFFA’s ® highly differentiated mechanism of action marks a critical step in understanding its interactions with Niemann-Pick disease type C (NPC) at a cellular level ...

and act via a previously unknown mechanism. In the newly published study, researchers led by Dr. Jennifer Herrmann and Prof. Rolf Müller uncovered the novel mode of action of chlorotonils.