U.S. Commercial Launch of ORLYNVAHTM by Q4 2025; First Oral Penem Available in the U.S. Management to host a conference call at ...

Zaynich is based on cefepime, a well-established beta-lactam antibiotic, combined with a novel beta-lactamase inhibitor ...

The OxStu discusses the causes and implications of antimicrobial resistance, and the social and scientific methods to combat ...

“Bacteria are clever,” Jutras said. “Strep and some other bacteria combat antibiotics by secreting beta-lactamases that inactivate piperacillin. We found the approach is totally irrelevant ...

These advancements contribute to the discovery of improved beta lactam antibiotics and beta lactamase inhibitors, addressing antimicrobial resistance and infectious diseases.

As the World Health Organization and others pine for new innovation in antibiotics, a combination option from Venatorx Pharmaceuticals and Melinta Therapeutics won't be able to help out the cause ...

MALVERN, Pa. & PARSIPPANY, N.J.--(BUSINESS WIRE)--Venatorx Pharmaceuticals (Venatorx) and Melinta Therapeutics (Melinta) announced today that the U.S. Food and Drug Administration (FDA) issued a ...

which are enzymes capable of hydrolyzing carbapenem antibiotics and most other beta-lactams and fall into two distinct families: serine beta-lactamases and metallo-beta-lactamases (MBLs).

This kills the bacteria. Some bacteria produce beta-lactamase, an enzyme that can damage penicillin and block its effects. To stop this from happening, penicillins may be combined with substances ...