Zaynich is based on cefepime, a well-established beta-lactam antibiotic, combined with a novel beta-lactamase inhibitor ...

Among children treated with an oral agent, the recurrence rate was 16/42 (38.1%) following penicillin or amoxicillin and 10/36 (27.8%) following a beta-lactamase resistant agent (adjusted odds ...

The OxStu discusses the causes and implications of antimicrobial resistance, and the social and scientific methods to combat ...

Winston Churchill's push to obtain penicillin in time to treat casualties expected from D-Day has come to light in documents seen by BBC News. Official papers unearthed by the National Archives ...

The FDA has approved GSK's gepotidacin, the first oral antibiotic to offer a new mechanism of action in uncomplicated urinary tract infections (uUTIs) in nearly 30 years, after a priority review.

Group I β-lactamases are major resistance determinants to β-lactam antibiotics. Despite intense study, the identity of the catalytic base, the direction of hydrolytic attack, and the functional ...

§ Faculty of Science, Health and Education, University of the Sunshine Coast, Maroochydore, DC, Queensland 4558, Australia, ∥ School of Population Health ...