Northwestern Medicine scientists have developed a promising approach to killing treatment-resistant cancer cells by ...

It has been known that MEHP has an impact on lipolysis; however, its mechanism on the cellular lipid metabolism remains largely unclear ... The CETSA identified 18 proteins and fatty acid β-oxidation ...

Lipids serve several important physiologic ... They are broken down in a beta-oxidation reaction and then enter the Kreb's cycle with subsequent production of adenosine triphosphate.

Interestingly, skeletal muscle ACOT2 knockout mice on chow and high-fat diet utilized more glucose during the active (dark cycle ... of the lipid oxidation pathway to metabolize the lipids. These ...

Here, we aim to provide an overview of recent studies using alkyne lipids to trace lipid metabolism by MS. Advantages and limitations ... these preparatory steps are followed by the actual β-oxidation ...

Metabolism comprises of ... and the fatty acids are broken down by beta oxidation to release acetyl-CoA. This acetyl co-A reaches the citric acid cycle next. Fatty acids release more energy ...

Glucose and fatty acids are essential substrates for ATP and biomass production; however, the metabolism ... body oxidation. Targeted metabolite profiling revealed that carbon from ketone bodies got ...

Through transcriptomic analyses of lipid pathways in human and rat pancreatic islets, the researchers revealed how a cycle of fat storage and mobilization (the glycerolipid/NEFA cycle) helps beta ...

Whether and how microRNAs are involved in the substrate selection for oxidation is largely unknown ... 96 as master regulators of fuel usage by coordinating both glucose and lipid metabolism in ...

Long chain fatty acid oxidation disorder (LCFAOD) is a group of genetic metabolic disorders characterized by impaired fat metabolism and energy deficiency ... 5 Research has shown that bezafibrate, a ...