Here we use cryogenic electron microscopy to determine the structure of TbAQP2 from Trypanosoma brucei, bound to either the substrate glycerol or to the sleeping sickness drugs, pentamidine or ...

4 Laboratory of Genetics, Immunology and Human Pathologies, Faculty of Sciences of Tunis, El Manar University, 2092 Tunis, Tunisia 5 Molecular Modeling Unit, Pasteur Institute of Tunis, 1002 Tunis ...

Aquaporins (AQPs) are integral membrane proteins and found in all living organisms from bacteria to human. AQPs mainly involved in the transmembrane diffusion of water as well as various small solutes ...

Introduction Clostridioides difficile infection (CDI), the leading cause of hospital-acquired diarrhoea, is primarily driven by two potent toxins, TcdA and TcdB. However, the molecular mechanisms ...

Scientists have found microplastics in human semen and follicular fluid, according to new research on a small group of adults ...

When tested on their own and in mice, these bacterial strains from the human microbiome show promise in accumulating PFAS ...

New research presented at the 41st Annual Meeting of the European Society of Human Reproduction and Embryology (ESHRE) ...

Aquaporins are integral membrane proteins that facilitate the rapid, selective transport of water—and in certain cases, small solutes such as glycerol—across cell membranes. In insects, these ...

Aquaporins are integral membrane proteins traditionally known for mediating water transport across cell membranes. Over recent decades, research has expanded their recognised roles to include the ...

According to a May publication in the Journal of Wildlife Diseases, researchers at UH Mānoa and the College of Tropical ...

Growing interest in health and the exposome—a person's collective environmental exposures—is spurring new funding and ...

In terms of quantity, the stool samples contained, on average, 20 particles of plastic, ranging in size from 50 to 500 micrometers. (For comparison, a human hair is about 100 micrometers thick.) ...