Here we use cryogenic electron microscopy to determine the structure of TbAQP2 from Trypanosoma brucei, bound to either the substrate glycerol or to the sleeping sickness drugs, pentamidine or ...

Seropositivity for aquaporin-4-specific antibodies (AQP4-Ab) is firmly established as a defining characteristic of neuromyelitis optica (NMO), a demyelinating disease that predominantly affects ...

Mitochondria are cell organelles surrounded by a double membrane. In addition to numerous essential functions in the ...

What if humans didn’t have to suffer the slow-burning fire of chronic inflammation as we age? A surprising study on two types of lemurs found no evidence of "inflammaging," a phenomenon long assumed ...

A previously unknown structure discovered in our cells could pave the way toward new treatments for various genetic disorders ...

Modifications in proteins after they are synthesized (post-translational) are changes that play a fundamental role in cell regulation, as they can alter biological activity and influence various ...

Supporters saw the Mütter’s preserved fetuses, skulls, and “Soap Lady” as a celebration of human difference. New management saw an ethical and a political minefield.

Background Data regarding long-term recovery from autoimmune encephalitis (AE) remain limited. Methods This retrospective ...

Anatomical position is a specific body position used when describing human anatomy. It’s often used by healthcare professionals to help discuss parts of the body in a clear and consistent manner.