We describe the incidence, location, and severity of bleeding with apixaban and warfarin in the ARISTOTLE trial. Methods: Major bleeding was defined as overt bleeding with a decrease in hemoglobin of ...

Although rivaroxaban demonstrably increases intracranial bleeding risk compared with aspirin, the comparative risk of intracranial hemorrhage with apixaban versus aspirin remains uncertain. We aimed ...

A recently started trial in the USA (RENAL-AF, clinicaltrial.gov identifier NCT02942407) comparing apixaban (5 mg twice daily) with warfarin (INR 2–3) in patients with AF and ESKD on haemodialysis ...

In addition, an unfinished phase II clinical trial has been conducted to evaluate the proper dose of ISIS-factor ⅪRX and compare the safety and efficacy of the study drug to apixaban in end-stage ...

Different classes of pain relievers work in different ways. Here’s how to figure out the ideal one for you. Ask Well Different classes of pain relievers work in different ways. Here’s how to ...

Although many patients requiring long term anti-thrombotic therapy now can be treated with direct oral anticoagulants (DOACs), vitamin K antagonists, such as warfarin, remain the only treatment option ...