New meta-analysis finds oral anticoagulants reduce net adverse events in patients with atrial fibrillation after intracranial hemorrhage but with a higher risk for recurrent intracranial hemorrhage.

Medically reviewed by Patricia Mikula, PharmD Coenzyme Q10 (CoQ10), a naturally occurring antioxidant, is also a popular supplement. As with any supplement, CoQ10 can interact with some medications.

Investigators studied apixaban pharmacokinetics, pharmacodynamics, and hemorrhage risk by kidney function. Kidney function is a major predictor of hemorrhage among patients with atrial fibrillation ...

Further trials comparing aspirin with newer anticoagulants (dabigatran, apixaban and rivaroxaban) are necessary to assess the role of each agent in stroke prevention in patients with AF.