Investigators studied apixaban pharmacokinetics, pharmacodynamics, and hemorrhage risk by kidney function. Kidney function is a major predictor of hemorrhage among patients with atrial fibrillation ...

Apixaban and dabigatran have been dosed twice daily and rivaroxaban once daily in Phase III clinical trials to date. [61, 69, 81, 82] There appears to be less peak-to-trough variation with twice ...

Patients were randomized to receive (1) one of six dosages of oral apixaban (5, 10, or 20 mg once daily or 2.5, 5, or 10 mg twice daily) starting 12–24 hours after surgery, (2) enoxaparin sodium ...

If the combination of apixaban and strong CYP3A4 inhibitors is unavoidable, reduce the dose of apixaban by 50% if on a regimen of 5 to 10 mg by mouth twice daily. 2 Concomitant use is not recommended ...

BackgroundThe introduction of non–vitamin K antagonist oral anticoagulants has been a major advance for stroke prevention in atrial fibrillation; however, outcomes achieved in clinical trials may not ...

Armed with the most advanced fitness wearable in existence, we set out to see what all the WHOOP 5.0 hype is about ...

The new-generation MG HS has been electrified and equipped with an all-new plug-in hybrid system. Zane Dobie has spent some time driving the pre-production Super Hybrid system before its ...