A phase three clinical trial is being conducted here to evaluate the safety and efficacy of a new quadrivalent dengue vaccine ...

Dengue fever, a mosquito-borne viral illness caused by the dengue virus (DENV), poses a significant public health threat in ...

A new study shows that Aedes aegypti, the mosquito responsible for spreading dengue, yellow fever and Zika, can still find human targets even after losing its sense of smell. At the same time, Indian ...

Recovery from infection provides lifelong immunity against a particular infecting serotype. However, immunity to the other serotypes is partial. Successive infections by other serotypes increase the ...

Antibodies to dengue can increase the virus’s infectivity for certain types of immune cells through a process called antibody-dependent enhancement (ADE), resulting in the production of more virus and ...

During secondary dengue infections, suboptimal levels of cross-reactive antibodies, mainly directed against the structural protein E, can drive antibody-dependent-enhancement of infection, resulting ...

Background: Infants born to dengue-immune mothers acquire maternal antibodies to dengue. Maternal antibodies decline over time, making infants susceptible to primary dengue infections. Another ...