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Antibodies are a major component of adaptive immunity against invading pathogens. In this presentation, we will describe an analytical approach to characterize the antigen-specific antibody repertoire ...
The method utilises a “structure-to-sequence” computer algorithm ... used high-resolution cryo-EM to rapidly and precisely map where antibodies in rhesus macaque monkeys bind to synthetic ...
The protein one is seeking an antibody to is screened against this random sequence array and peptides ... desired protein for binding affinity and a map is produced displaying this affinity ...
The ability to obtain antibody RNA sequences and map these sequences back to the single B cells from which they came was not only higher-throughput than previous approaches; it also allowed them to ...
Researchers show that analyzing the 3D shapes of antibodies, not just their genetic sequences, can better group functionally ...
At the core of their LENSai platform is a comprehensive and continuously expanding knowledge graph that maps 25 billion relationships across 660 million data objects, linking sequence, structure ...
the scientists first needed to map the route. They began by turning to an existing technology to sequence the collection of B-cell genes that code for all the antibodies created by a person's ...
An antibody comprising an amino acid sequence having at least a 90% sequence identity to SEQ ID NO:1. The antibody of claim 1, wherein the amino acid sequence comprises the sequence of SEQ ID NO ...
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