Objectives The association between ambient heat and neural tube defects has received limited attention, despite imminent climate warming this century. We sought to determine the relationship between ...

A numerical example of the calculations is given using some anencephalus data, and the results are compared with those of alternative tests.

This is not the case for the anencephalus result. Increased risks of central nervous system defects in general, however, were not found. An association between anencephaly, spina bifida, and other ...