Particularly concerning are infections caused by highly resistant strains with ESBL and AmpC-producing Enterobacteriaceae (AmpC-E) and Carbapenemase-producing Enterobacterales (CPE), which are ...

Alembic to expand their U.S. commercial portfolio with FDA-approved PIVYA for the treatment of women with uncomplicated ...

However, resistance due to plasmid-mediated AmpC enzymes is less common than ESBL production in these organisms in most parts of the world. Since strains with AmpC genes are often MDR, ...

To become resistant, bacteria typically need to change particular genes like ampC in specific ways. To become tolerant, they just need to slow their growth, and there are many genes they could ...

There are several potential β-lactamase inhibitors under investigation, in different stages of preclinical and clinical trials. Although the results of Phase I and II studies were mostly not ...

Extended spectrum beta-lactamase (ESBL) and AmpC-producing Enterobacteriaceae (AmpC-E), which are resistant to a number of commonly used antibiotics, have become a matter of great concern in both ...

Extended spectrum beta-lactamase (ESBL) and AmpC-producing Enterobacteriaceae (AmpC-E), which are resistant to a number of commonly used antibiotics, have become a matter of great concern in both ...

The researchers also found that some of the horses in the Quebec study were passing E. coli carrying the ESBL/AmpC genes responsible for cephalosporin resistance, which is particularly worrisome.

Areas with high socioeconomic disparities are more likely to have higher rates of resistant organisms. AmpC beta-lactamase Gram negative organisms and MRSA had the greatest amount of clustering.

UK/Portuguese study strongly suggests antibiotic-resistant “superbugs” are being passed from cats and dogs to their owners Go to source).