2011; Lee et al., 2012). Since self-assembling peptide amphiphiles often include amino acid side chains with weak acids like glutamic acid or aspartic acid (or weak bases like lysine), the extent of ...

The procedure within multisite extent of deprotonation originating from context (MEDOC) uses a database of context dependent ionization free energies, where each of the ionizable amino acid ...

Changes to the intermediate filament (IF) protein, vimentin, were found to promote tumor growth by increasing cancer stemness in an oestrogen independent manner. Targeting vimentin and/or the long ...

Synthetic biologists from Yale were able to re-write the genetic code of an organism - a novel genomically recoded organism (GRO) with one stop codon - using a cellular platform that they developed ...

Scientists have discovered that some tiny segments of RNA thought to be junk instead have a functional role in suppressing ...

Proteins are the workhorses that keep our cells running, and there are many thousands of types of proteins in our cells, each ...

Here we explore peptide inhibitors of Cdc20, a substrate-recognition subunit and activator of the E3 ubiquitin ligase the anaphase promoting complex/cyclosome (APC/C) that is essential in mitosis and ...