A drug that can be taken orally could soon rival the likes of Ozempic for treating type 2 diabetes and obesity, according to ...

This article reviews the current state of knowledge and understanding of the genetic variation present in the three human beta-adrenergic receptor genes.

Notably, the α 2a-adrenergic receptor is expressed in brain regions involved in pain modulation, and α 2a-adrenergic agonists (i.e., drugs that activate this receptor can alleviate chronic and ...

The addition of β-adrenergic receptor antagonists to a medical regimen for heart failure that includes angiotensin-converting enzyme (ACE) inhibitors as background therapy has been associated ...

G protein-coupled receptors (GPCRs) are integral membrane proteins with seven membrane-spanning helices. Upon binding to a ligand – which can range from small molecules like cyclic AMP to ...

Shane Wright, Assistant Professor at the Department of Physiology and Pharmacology, and colleagues have uncovered a new way ...

Using inhibitors of different subtypes of adrenergic receptors—α1-, α2-, and β-ARs—the scientists found that NE shushing synapses required only α1-ARs. This surprised them at first, because engagement ...