The addition of β-adrenergic receptor antagonists to a medical regimen for heart failure that includes angiotensin-converting enzyme (ACE) inhibitors as background therapy has been associated ...

The crystal structure of a second G protein–coupled receptor sheds light on these key pharmaceutical targets. In contrast, β2AR and essentially all of the other GPCRs are present at very low ...

The binding of adrenaline to an adrenergic receptor initiates a cascade of reactions inside the cell. The signal transduction cascade begins when adenylyl cyclase, a membrane- bound enzyme ...

Mice exhibit a well-documented circadian rhythm and ECG parameters comparable to humans, so the researchers pharmacologically blocked the SNS using the β-adrenergic receptor blocker, propranolol in ...

Ephedrine sulfate is a sympathomimetic amine that directly acts as an agonist at α-and ß-adrenergic receptors and indirectly causes the release of norepinephrine from sympathetic neurons.

Objective: To compare the haemodynamic effects of nebivolol, a highly selective antagonist of 1-adrenergic receptors with additional actions caused via the L-arginine/nitric oxide pathway ...

The β 2-Adrenergic receptor (Adrb2), which is a norepinephrine receptor, is expressed in various cells, including immune cells. In Adrb2 knockout mice, the stress-induced increase of IgE-CAI was ...

Propranolol reduces Parkinson’s tremor and motor cortex activity, suggesting a new therapeutic approach beyond stress ...

Propranolol HCl 60mg, 80mg, 120mg, 160mg; sust-rel caps. Propranolol, a nonselective β-adrenergic receptor blocker, does not possess autonomic nervous system activity. Propranolol generally ...