29 Moreover, adiponectin reduces the secretion of interleukin-6 (IL-6) from brain endothelial cells in response to oxidative stress, modulating BBB function. 30 Judging from previous evidences ...

Cultured human umbilical vascular endothelial cells (HUVECs) and osteoblasts were stimulated with adiponectin (1 or 10 μg ml −1) or IL-1β (0.1 ng ml −1) in the presence or absence of ...

Experimental and clinical studies suggest that there is an evolving role for endothelial progenitor cells in neoangiogenesis and rejuvenation of the endothelial monolayer. 6,12,17 The presence of ...

Red blood cell-derived extracellular vesicles in type 2 diabetes are actively taken up by the endothelium, transferring the ...

Adiponectin, a hormone secreted by adipose tissue, plays a doubly important role in preserving pancreatic function: in lean people, it protects beta cells, which make insulin, and in obese people, it ...

Cardiovascular risk factors contribute to atherogenesis by inducing endothelial-cell injury and dysfunction. We hypothesized that endothelial progenitor cells derived from bone marrow have a role ...

Researchers led by Maike Sander, Scientific Director of the Max Delbrück Center, have developed a vascularized organoid model of hormone secreting cells in the pancreas.