After birth, disruptions in Hippo signaling have been found to lead to de-differentiation of acinar cells and pancreatitis-like phenotype. Further, Hippo signaling directs pancreatic morphogenesis by ...

The ‘ food as medicine ’ trend is changing the way consumers view the entire food and beverage industry. Worth an estimated ...

Assays in β (and/or α)-cell-specific V1b KO mice and IP3R KO mice must be provided to support these speculations. In this paper, Drs. Kercmar, Murko, and Bombek make a series of observations related ...

Learn more about eLife assessments Highly spatio-temporally resolved imaging of islet Ca 2+ oscillations on pancreatic tissue slices provides ... Physiological glucose stimulation triggers non-linear ...

Pancreatic ductal adenocarcinoma (PDAC ... and metastatic sites. Myeloid cells, such as tumor-associated macrophages (TAMs) and myeloid-derived suppressor cells (MDSCs), play pivotal roles in shaping ...