Post-translational modifications (PTMs) are essential players in regulating protein functions, including stability, localization, and interactions, and they ...

However, the study could provide a discussion on the impact of the overlap of other post-translational modifications with Kacac sites with their implications on protein functions. Impact The authors ...

Lactylation, a recently identified post-translational modification, has emerged as important for immune regulation, tissue repair, cancer cell metabolism, and now, potentially, Alzheimer’s disease. In ...

Cancer, a disease with global impact, is intricately linked to dysregulated gene expression, which is influenced by both genetic mutations and epigenetic changes, including RNA modifications. A ...

Epigenetics involves a series of biological processes that regulate chromatin-mediated DNA templates. 2 Cancer is a ...

Post-translational modifications (PTMs) such as phosphorylation, acetylation, ubiquitination, SUMOylation (small ubiquitin-like modifier), neddylation, and oxidation are key regulatory mechanisms in ...

Opening of the "Life Sciences" lecture series with the main topic "Post-translational modifications" by Professor Dr. Elke Krüger (University of Greifswald) and Professor Dr. Michael Lammers ...

Post-translational modifications (PTMs)—the chemical changes that proteins undergo following biosynthesis—account for most protein forms, or proteoforms. Indeed, according to conservative ...

Abstract Phosphorylation and acetylation of sarcomeric proteins are important for fine-tuning myocardial contractility. Here, we used bottom-up proteomics and label-free quantification to identify ...

Additional Post-Translational (PTM) Modification Analysis In addition to phosphorylation sites on C4C5, the LC-MS/MS results were also searched for carbamidomethylation (oxidation) at M (methionine), ...

Acetylation is a key post-translational modification that integrates metabolic flux and physiological processes within cells, including circadian rhythm, cell cycle and energy production Lysine ...