News

ahajournals.org22h
Aortic Stress Activates an Adaptive Program in Thoracic Aortic Smooth Muscle Cells That Maintains Aortic Strength and Protects Against Aneurysm and Dissection in Mice
Administering AngII/HFD has been shown to induce aortic degeneration in thoracic and abdominal aortic segments in C57BL/6J WT mice, 15 along with the development of aortic dilatation (98%), AAD ...
ahajournals.org22h
Aortic Cellular Diversity and Quantitative Genome-Wide Association Study Trait Prioritization Through Single-Nuclear RNA Sequencing of the Aneurysmal Human Aorta
Contrary to prior single-cell studies of human aorta, no predominant immune cell population or novel infiltrative cell population was identified in aneurysm tissue. Findings emphasize the distinct ...