Recent evidence indicates that FNIP1 is implicated in mitochondrial biology through various pathways, including AMPK, mTOR, and ubiquitination, which regulate mitochondrial autophagy, oxidative stress ...
and the interaction between AKT and TSC2 activates downstream mTOR receptors. The TSC complex, consisting of TSC1 and TSC2, interacts with GTPase-Ras to serve as a negative regulator of mTOR activity.
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