Biofuels and Bioprocessing Research Center, Institute of Technical Education and Research, Siksha ‘O’ Anusandhan (Deemed to Be University), Bhubaneswar 751030, India ...

Aquaporins are proteins that rapidly transport water across cell membranes while excluding salt. They are critical for maintaining the right balance of water inside and outside cells and for ...

IgG4-RD is the second approved indication for inebilizumab-cdon. The first was its approval in 2020 for adults with anti-aquaporin-4 neuromyelitis optica spectrum disorder. The treatment is ...

Methods and results: We revealed that patients and mice with HUA had a polyuria phenotype and found that the expression of aquaporin 2 (AQP2), AQP3 and AQP4 were significantly reduced in the kidneys ...

Inebilizumab significantly reduced the risk of treated and AC-determined IgG4-RD flare by 87% compared with placebo. The Food and Drug Administration (FDA) has approved Uplizna ® (inebilizumab ...

Inebilizumab-cdon was previously approved by the FDA for neuromyelitis optica spectrum disorder (NMOSD) in adults who are anti-aquaporin-4 antibody positive, in 2020. It has also been designated ...

Research continues to elucidate the complex immunological processes underlying the pathophysiology of aquaporin 4-antibody seropositive (AQP4+) neuromyelitis optica spectrum disorder (NMOSD), ...

ADH reports that 78.3% of deaths due to flu were to people who were not vaccinated. The report also states that 13 people died due to COVID-19 for the week, and 65 died due to pneumonia. ADH added ...