While endogenous Cushing's syndrome can be caused by an adrenocorticotrophic hormone (ACTH)-dependent or ACTH-independent mechanism, it is most often a result of excess secretion of ACTH by a ...

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Tumours that secrete adrenocorticotropic hormone (ACTH) can overstimulate cortisol release and result in Cushing's syndrome. These tumours may be benign or malignant and are frequently located in ...

Introduction: ACTH-dependent Cushing syndrome (CS) is a rare endocrine disease including Cushing disease (CD), ectopic ACTH syndrome (EAS) and ectopic corticotropin-releasing hormone (CRH) syndrome.

Cushing (1869-1939). The recognition that glucocorticoid excess ... pressure despite blockade of cortisol-induced hyperinsulinemia. In experimental studies of ACTH-induced hypertension in the rat ...

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Salivary cortisol measurements are particularly useful to investigate cyclical Cushing's syndrome. At least partial autonomy of cortisol production (either direct from the adrenal cortex or ...