Two key protein structures in the body are being visualized for the first time, thanks in part to the latest technology in the University of Cincinnati's Center for Advanced Structural Biology ...

On closer inspection, many of the messenger RNA molecules did not correspond to any known gene. Previously unknown genes were making previously unknown proteins.

Besides, multiple ABO mutations carriers were less likely to experience diarrhea (P -value = 0.023). Conclusions: our findings showed that the multiple ABO mutations carriers did not suffer more irAEs ...

Title: ARCUS-Mediated Gene Editing Excision of Exons 45-55 of the Human Dystrophin Gene using PBGENE-DMD Leads to Functional Dystrophin Protein and Durable Restoration of Skeletal Muscle-Function ...

About ABO-101 ABO-101 is a novel, investigational gene editing medicine designed to be a one-time liver-directed gene editing treatment that results in a permanent loss of function of the HAO1 ...

Scientists have for the first time looked deep into the protein structure that may determine our vision - and discovered that it is much more dynamic than previously thought.

The physical interactome of a protein can be altered upon perturbation, modulating cell physiology and contributing to disease. Identifying interactome differences of normal and disease states of ...

Researchers say structure reveals many new ways to change PINK1, essentially switching it on, which will be "life-changing" for people with Parkinson’s disease.

Here, we introduce the Interpretable protein-DNA Energy Associative (IDEA) model, a predictive model that learns protein-DNA physicochemical interactions by fusing available biophysical structures and ...

Protein structure Medications often target enzymes to regulate biochemical processes in the body. Understanding the structure of proteins is a key to understanding enzyme function, as almost all ...

AlphaFold solved a structural biology riddle: predicting protein structure. And yet, CASP, a global competition born to solve that problem, lives on.