We thank Audrey R. Odom John, currently the Stanley Plotkin Chair of Pediatric Infectious Diseases and Chief of the Division of Pediatric Infectious Diseases at the Children’s Hospital of Philadelphia ...

Scientists have elucidated the molecular mechanism by which LEM-3 cuts DNA bridges during cytokinesis ... LEM-3 is a nuclease, and nucleases act like a surgical knife on DNA.

and IBS Research Fellow Stephane ROLLAND announced that they have elucidated the molecular mechanism by which LEM-3 cuts DNA bridges during cytokinesis. Cell division is an essential biological ...

If DNA bridges persist between chromosomes during cell division ... bridges and subsequent cell division failure. LEM-3 is a nuclease, and nucleases act like a surgical knife on DNA.

During cytokinesis in human cells, a failure to resolve persistent DNA bridges that span the cell-division plane maintains the Aurora B-dependent abscission checkpoint in an active state. However, the ...

A new study shows that even a moderate dose of caffeine alters brain activity during sleep, increasing complexity and nudging neural systems toward a high-efficiency processing state, especially ...

During a solar eclipse in a forest in Italy’s Dolomites region, scientists seized the chance to explore that fascinating question. The researchers were monitoring the bioelectrical impulses of ...

On the West Coast, this event will occur during convenient mid-to-late evening hours. How about staging a neighborhood eclipse party? Conversely, for those across the Atlantic, the eclipse will ...

Toward the goal of efficient editing of farm animals for genetic improvements, this study explores an upgraded form of nuclease PE (uPEn). Based on an initial demonstration of its success in ...

Now, new preclinical research presents the discovery and engineering of NanoCas—an ultracompact CRISPR nuclease capable of extending CRISPR’s reach in vivo beyond liver targets. NanoCas is the ...

The Dystrophin-associated protein complex promotes cytokinesis efficiency. Dystrophin and Dystroglycan show dynamic cortical redistribution during and post cytokinetic ring constriction. Dys and Dg ...