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T cells are the immune system’s frontline fighters. When they detect danger, they rapidly multiply and transform into ...
Infections caused by herpes simplex virus type 1 (HSV-1) can lead to HSV-1 encephalitis-a rare but deadly condition that ...
At some point, RNA must have replicated itself before the evolutionary arrival of DNA and proteins, and now we might know how ...
A protein called PriC allows DNA replication to proceed in Escherichia coli when the complex that usually initiates this process is compromised.
Chemists have demonstrated how RNA (ribonucleic acid) might have replicated itself on early Earth -- a key process in the origin of life.
With increasing demand for DNA replication enzymes-based diagnostics ... According to BIS Research, the global ligase market is projected to reach $651.4 million by 2032, up from $371.2 million in ...
Another significant finding of this study was the interaction between TEFM and the DNA polymerase γ (POLG), an essential enzyme involved ... H-strand replication origin of mtDNA. Commun Biol. 2025;8(1 ...
Brandt Eichman and Walter Chazin, professors of biochemistry, have worked together to provide a better understanding of how exactly DNA replication ... primase), the enzyme responsible for ...
The importance of these enzymes in maintaining genome homeostasis is ... followed by incubation with hydroxyurea (HU, 4 mM) for stalling DNA replication forks. Cells were subjected to fixation with a ...
Schematic representation of the bacteriophage Φ29 DNA replication mechanism ... 2007; del Prado et al., 2012). Figure 4. Comparison of the binary (yellow) and ternary (green) complex structures of Φ29 ...
Enzymes that cut DNA at specific sites are called endonucleases; these enzymes play many roles in genomic replication, fidelity ... This domain separation enables retention of the 4-7 nucleotide ...